These are a series of hands-on practical workshops on bioinformatics- and genomics-related topics. Workshops started in January 2004, and now occur at least twice a year, and cover topics such as sequence analysis, Unix, Python and R. These workshops are a collaborative effort between the Applied Bioinformatics Core at Weill Cornell Medicine and the Bioinformatics Core at Memorial Sloan Kettering and are open to all faculty, staff and fellows for a nominal fee, and are free for students. All workshop materials are available online at: http://www.trii.org/courses/.